Sarsaparilla root

Tier 3 — weak evidence · Inflammation · Hormonal · Gut detox

A tropical vine root (Smilax officinalis) traditionally used for inflammatory joint conditions, skin conditions, and hormonal balance. Contains steroidal saponins (sarsasapogenin, smilagenin) that bind gut endotoxins — potentially explaining documented liver-protective effects. Some evidence for anti-inflammatory activity via COX inhibition. Popularised as a testosterone booster in bodybuilding circles — this claim has no credible evidence. Better supported as an anti-inflammatory and gut-endotoxin binding agent.

Dose: 300–600 mg dried root extract twice daily