Oxiracetam

Tier 3 — weak evidence · Nootropic · Memory · Focus

A water-soluble racetam nootropic with mild stimulant properties. Enhances hippocampal long-term potentiation in animal models. Small clinical trials in dementia patients showed modest improvements in memory and attention. Not approved in the US. Better studied than many racetams but evidence remains limited. More stimulating than piracetam but less than phenylpiracetam.

Dose: 800–2,400 mg/day in 2–3 divided doses; water-soluble so no fat needed for absorption