Nootropic peptide selank (synthetic)

Tier 3 — weak evidence · Nootropic · Anxiety · Synthetic peptide

A synthetic heptapeptide analogue of tuftsin developed at the Russian Institute of Molecular Genetics. Approved as an anxiolytic nasal spray in Russia. Acts on GABA and serotonin systems without sedation or dependence. Multiple Russian trials report significant anxiety reduction and cognitive enhancement. Lacks Western regulatory approval and independent replication outside Russia.

Dose: 250–500 mcg/day intranasal; approved only in Russia; no Western regulatory approval