Monolaurin

Tier 3 — weak evidence · Antimicrobial · Immunity · Gut

A coconut-derived monoglyceride with antimicrobial activity against enveloped viruses and gram-positive bacteria in lab studies. Very few human trials exist; most evidence is extrapolated from in vitro or lauric acid research. No rigorous RCTs confirm specific clinical benefits. Generally safe. Herxheimer-like reactions can occur early in use — start at a low dose.

Dose: 600–1,800 mg/day; start low (300 mg) to avoid Herxheimer-like reactions