MitoQ

Tier 2 — promising · Mitochondrial · Antioxidant · Ageing

A mitochondria-targeted ubiquinone conjugated to a lipophilic triphenylphosphonium cation, causing it to accumulate 1000-fold inside mitochondria compared with standard CoQ10. Multiple human RCTs show improvements in vascular endothelial function in older adults, reduced fatigue in relapsing MS, and reduced ICU-acquired weakness markers. The targeted delivery matters more than the total antioxidant capacity — unlike conventional antioxidants, MitoQ acts precisely where ROS are generated.

Dose: 10–20 mg/day on an empty stomach