DHEA (Dehydroepiandrosterone)

Tier 3 — weak evidence · Hormonal · Aging · Adrenal

A precursor hormone your adrenal glands produce that declines with age. A 2024 review found modest bone density improvements in postmenopausal women. Banned in competitive sports by most organizations. Can raise both estrogen and testosterone levels, so it requires regular hormone monitoring by your doctor. Not recommended for healthy adults.

Dose: 25–50 mg/day in adrenal insufficiency only; not recommended for healthy adults; banned in competitive sports