Spore-based probiotics (Bacillus coagulans)
Tier 2 — promising · Gut health · IBS · Resilience
Spore-forming probiotics survive stomach acid and shelf storage better than traditional strains, so they don't need refrigeration. Bacillus coagulans has the strongest evidence among spore-based probiotics, with multiple trials showing reduced IBS symptoms and improved gut barrier function. Generally well tolerated with no major side effects.
Dose: 1–2 billion CFU/day; survives stomach acid without enteric coating