2'-Fucosyllactose (2'-FL HMO)

Tier 2 — promising · Gut health · Immunity · Microbiome

The most abundant human milk oligosaccharide (HMO), now synthesised via fermentation and available as an adult gut health ingredient. 2'-FL selectively feeds Bifidobacterium longum and promotes a health-associated microbiome. Clinical trials in adults show reductions in upper respiratory infection duration, improved gut barrier markers, and reduced GI illness severity. Mechanistically it acts as a decoy receptor for pathogens including H. pylori and norovirus.

Dose: 1–5 g/day in water or a beverage