R-Alpha lipoic acid

Tier 3 — weak evidence · Neuropathy · Blood sugar · Antioxidant

The natural R-form of alpha lipoic acid, which is more bioavailable than the synthetic racemic mix commonly sold. Multiple trials show it reduces diabetic neuropathy symptoms like numbness, tingling, and burning pain. Also supports healthy blood sugar levels. Take on an empty stomach for better absorption. May lower thyroid hormone at very high doses.

Dose: 300–600 mg/day R-ALA; take on an empty stomach for better absorption