Oyster mushroom extract (Pleurotus ostreatus)

Tier 3 — weak evidence · Cholesterol · Immunity · Antioxidant

Contains lovastatin naturally, the same compound in prescription statin drugs. Small trials show modest cholesterol reduction and immune stimulation. The extract delivers higher beta-glucan concentrations than eating the mushroom. Very safe as food; evidence as a supplement is limited. Additive with statin drugs.

Dose: 500–1,000 mg/day extract or 10–15 g/day fresh mushroom; contains natural lovastatin — additive effect with statin drugs