Manuka honey (medicinal grade)

Tier 3 — weak evidence · Wound healing · Antimicrobial · Gut

Has strong Cochrane-supported evidence for wound healing when applied topically as medical-grade honey. However, oral supplement claims for gut health and immunity are not supported by human trials. Quality varies widely based on MGO content (UMF 15+ is medical grade). The topical use is legitimate, but oral supplements are not well supported.

Dose: Topical wound use: medical-grade UMF 15+ honey applied to cleaned skin under a non-adherent dressing, changed daily. Oral throat-soothing use: 1 teaspoon (~5 g) UMF 10+ as needed for sore throat (limited evidence). No evidence-based oral dose for systemic health claims.