Calendula (Calendula officinalis)

Tier 2 — promising · Wound healing · Skin · Anti-inflammatory

Best known for topical wound healing and skin inflammation with reasonable clinical evidence for dermatitis and radiation-induced skin damage. Oral supplement evidence is very limited. EMA approves topical calendula for minor wounds and inflammation. The oral supplement form has almost no clinical trials. Very safe both topically and orally. Avoid if allergic to plants in the daisy family.

Dose: Topical: cream/ointment for wounds (evidence-based). Oral: 500–1,000 mg/day extract (limited evidence)