Magnesium orotate

Tier 3 — weak evidence · Cardiovascular · Athletic · Energy

Combines magnesium with orotic acid, which plays a role in cellular energy and heart muscle function. A few older European studies suggest benefit for heart failure. The most expensive magnesium form with the least general-use evidence. Rarely justified over glycinate, citrate, or malate forms for most people.

Dose: 400–800 mg/day magnesium orotate; expensive with limited evidence advantage over other forms