Hyaluronic acid + Chondroitin stack

Tier 2 — promising · Joint · Skin · Connective tissue

A combination of oral hyaluronic acid and chondroitin sulfate to support joint lubrication and cartilage integrity. A 2024 trial found the combination modestly reduced knee stiffness and improved mobility after 3 months. Evidence for each component individually is modest. Very safe with no known drug interactions.

Dose: 80–200 mg/day low-MW hyaluronic acid + 400–800 mg/day chondroitin sulfate; allow 3 months