Higenamine (norcoclaurine, pre-workout)

Tier 4 — risky / avoid · Cardiac arrhythmia · Banned stimulant · Pre-workout

A beta-adrenergic agonist found in some pre-workout and fat-burning supplements. Banned by WADA in 2017 due to stimulant properties. Causes dose-dependent increases in heart rate and blood pressure with risk of cardiac arrhythmias. FDA issued warnings about supplements containing higenamine. Often undeclared on labels — found in products containing aconite, lotus seed, or Nandina. No evidence it enhances exercise performance.

Dose: AVOID — banned by WADA; causes cardiac arrhythmias; often undeclared in pre-workout supplements