California poppy (Eschscholzia californica)

Tier 3 — weak evidence · Anxiety · Sleep · Mild sedation

A gentle sedative herb used in European herbal medicine for mild anxiety and sleep difficulties. Contains alkaloids that modulate GABA and opioid receptors at very low potency. EMA classifies it as a traditional herbal medicine for mild nervous tension and sleep. Very few clinical trials exist, with most evidence based on traditional use. Non-addictive and very safe at recommended doses.

Dose: 300–600 mg/day extract or 2–3 cups tea before bed; traditional use — limited clinical trial data