Bifidobacterium infantis EVC001

Tier 1 — strong evidence · Probiotic strain · Pediatric · Breastfed infant

EVC001 (Evivo) is a specific strain of Bifidobacterium longum subsp. infantis uniquely capable of metabolising all human milk oligosaccharides (HMOs). It addresses a modern infant gut dysbiosis: bifidobacteria have become rare in Western infants, leaving the neonatal microbiome without their protective acidifying effect. Henrick et al. 2019 (Pediatric Research, PMID 31443102) — an RCT — showed EVC001 supplementation significantly lowered fecal calprotectin and pro-inflammatory cytokines in exclusively breastfed infants. Henrick et al. 2021 Cell (PMID 34143954), a Cell-published RCT,…

Dose: 1.8 × 10^8 CFU/day (commercial Evivo dose) mixed into a small amount of expressed breastmilk and fed by syringe or spoon for the first 100 days of life. Do not mix into a full bottle.