Yellow oleander (Thevetia peruviana)

Tier 4 — risky / avoid · Cardiac glycoside · Fatal arrhythmia

Every part of this ornamental plant contains thevetin, a cardiac glycoside similar to digoxin that causes fatal heart rhythm disturbances. Used in traditional medicine in some regions and as a means of self-harm in South Asia. A single fruit can contain a lethal dose. There is no safe way to prepare or consume it as a supplement. Symptoms progress rapidly from nausea to fatal cardiac arrest.

Dose: AVOID — a single fruit can be lethal; causes fatal cardiac arrhythmia; no safe dose exists