Plant ceramides

Tier 2 — promising · Skin · Gut barrier · Hydration

Ceramides are structural lipids essential for skin barrier integrity and gut epithelial function. Plant-derived ceramides (from wheat gliadin, konjac, or rice bran) can be incorporated into skin membranes after oral ingestion. A French RCT using wheat-derived ceramides showed significant improvements in skin hydration, smoothness, and elasticity within 3 months. Emerging gut barrier data is also encouraging. A novel but biologically plausible supplement category with an excellent safety profile.

Dose: 30–200 mg/day wheat gliadin ceramide complex with a fat-containing meal