Phenibut

Tier 4 — risky / avoid · GABAergic · Dependence · Withdrawal

A synthetic drug developed in the Soviet Union that creates strong calming and euphoric effects by acting on GABA receptors. Physical dependence can develop in as little as 3 to 5 days of daily use. Withdrawal is severe and can be life-threatening, mimicking benzodiazepine withdrawal with seizure risk requiring hospitalisation. Not approved as a supplement anywhere in the US, EU, or Australia.

Dose: AVOID entirely — physical dependence within days; life-threatening withdrawal; not approved anywhere as a supplement