Peptide secretagogues (GHRP/ipamorelin)

Tier 4 — risky / avoid · Unapproved peptide · Banned by WADA · GH secretion · Cancer risk · Injection

Synthetic peptide compounds including GHRP-2, GHRP-6, ipamorelin, CJC-1295 (non-DAC), and hexarelin that stimulate pituitary growth hormone release. Not approved for human use — sold online as "research peptides" and used illicitly in performance sports and anti-aging clinics. Side effects include insulin resistance (GH impairs glucose uptake), carpal tunnel syndrome, joint swelling, water retention, and theoretical cancer promotion (GH and IGF-1 are growth factors for most cancers). Banned by WADA and most sports organisations. Sermorelin is the only growth hormone secretagogue approved…

Dose: AVOID self-administration — GHRP-2, GHRP-6, ipamorelin, and CJC-1295 are unapproved drugs in all jurisdictions; only sermorelin is approved, by prescription only