Methylsynephrine (oxilofrine)

Tier 4 — risky / avoid · Stimulant · Banned · Risky

Pharmaceutical β-1 adrenergic agonist (oxilofrine) sold off-label as a weight-loss / pre-workout 'stimulant' under various synonyms (methylsynephrine, hydroxyephrine, p-hydroxyephedrine). FDA warned manufacturers; multiple case reports of adverse cardiac events. Banned by WADA/NCAA. Avoid.

Dose: AVOID