Lumbrokinase

Tier 3 — weak evidence · Fibrinolysis · Circulation · Cardiovascular

A fibrinolytic enzyme extracted from earthworms that dissolves fibrin, a protein involved in blood clotting. Similar mechanism to nattokinase but potentially more potent. Small clinical trials show it reduces fibrinogen levels and improves blood viscosity. Used extensively in Traditional Chinese Medicine. Do not combine with blood thinners as it significantly increases bleeding risk.

Dose: 40–80 mg/day (600,000–1,200,000 IU); AVOID with anticoagulants — additive bleeding risk