Lithium orotate (low-dose)

Tier 3 — weak evidence · Mood · Neuroprotection · Longevity

Different from prescription lithium, which is used at much higher doses for bipolar disorder. Small population studies suggest brain-protective effects at very low doses, but very few human trials exist. No established therapeutic dose or safety profile. Consider this entirely experimental. Do not combine with prescription lithium without medical supervision.

Dose: 1–5 mg/day lithium orotate (experimental use only; no evidence-based dose established)