Gamma-tocopherol

Tier 2 — promising · Vitamin E · Cardiovascular · Anti-inflammatory

The predominant tocopherol form in the American diet and the vitamin E isomer most effective at quenching reactive nitrogen species (peroxynitrite) — a role alpha-tocopherol cannot fulfil. High-dose alpha-tocopherol supplementation displaces gamma-tocopherol from tissues, potentially explaining the null or negative cardiovascular results in isolated alpha-E trials. Mixed-tocopherol supplements or gamma-enriched products restore physiological balance. Strong evidence for reducing inflammatory markers in metabolic syndrome.

Dose: 100–200 mg mixed tocopherols (gamma-predominant) daily