Fadogia agrestis

Tier 3 — weak evidence · Testosterone · Libido · Athletic

A Nigerian shrub widely promoted by social media influencers as a testosterone booster. Only animal studies exist — no human trials have been published. Animal studies showed elevated testosterone but also dose-dependent testicular toxicity (shrinkage and damage). This safety concern has never been evaluated in humans. Using a supplement with zero human safety data is a genuine risk.

Dose: Not recommended — zero human clinical trials; animal studies show testicular toxicity; safety unestablished