Coriolus versicolor PSP/PSK (turkey tail polysaccharide)

Tier 2 — promising · Immunity · Cancer adjunct · Gut microbiome

PSK (Krestin) is an approved adjunctive cancer treatment in Japan with over 30 years of clinical use. PSP is a related polysaccharide from the same mushroom. Multiple trials show improved 5-year survival rates in gastric and colorectal cancer when used alongside conventional treatment. A 2024 trial also found PSP significantly improved gut microbiome diversity. Not a standalone cancer treatment.

Dose: 1,000–3,000 mg/day PSK or PSP standardised extract; studied as adjunct to conventional cancer treatment, not standalone