Cissus quadrangularis

Tier 3 — weak evidence · Bone healing · Joint · Weight

Helps speed up bone fracture healing and reduces arthritis joint pain. A 2024 review of 9 trials confirmed these benefits with clinical significance. A traditional Ayurvedic plant now backed by modern clinical evidence. The standardized extract form (3% ketosterones) has the most research. Generally well tolerated with a good safety profile.

Dose: 500–1,000 mg/day standardised extract (3% ketosterones)