Calcium pantothenate (Vitamin B5)

Tier 2 — promising · Vitamin B5 · Adrenal · Skin

The calcium salt of pantothenic acid, the stable and well-absorbed common supplemental form of vitamin B5. Essential for coenzyme A synthesis and acyl-carrier protein function — central to fatty acid metabolism, steroid hormone synthesis, and neurotransmitter production. High-dose pantothenic acid (2-10 g/day) has evidence for reducing acne vulgaris. Claims around 'adrenal support' in stress are mechanistically plausible but clinically unproven. Very safe even at high doses; diarrhoea is the main limit.

Dose: 50–500 mg/day general use; up to 2–5 g/day split doses for acne