Astragaloside IV (isolated)

Tier 3 — weak evidence · Telomere · Anti-aging · Immunity

A purified compound from astragalus root promoted as a telomerase activator. Cell and animal studies show telomere-related effects, but no published human RCTs exist. The effective human dose is unknown. Extremely expensive with no clinical dose established. Short-term safety data is reassuring, but long-term human data is completely absent.

Dose: 5–50 mg/day of isolated astragaloside IV; no established human clinical dose; very expensive