7-Keto DHEA

Tier 3 — weak evidence · Metabolism · Weight · Thermogenesis

A DHEA metabolite that does not convert to testosterone or estrogen, avoiding hormonal side effects. Two small trials found 200 mg/day plus exercise increased metabolic rate and produced modest fat loss over placebo. Not banned in sport. Fewer than 5 published human trials exist. Generally safe at tested doses.

Dose: 100–200 mg/day; does NOT convert to sex hormones unlike regular DHEA; very limited human evidence