7-Hydroxymitragynine (concentrated kratom alkaloid)

Tier 4 — risky / avoid · Opioid agonist · Concentrated kratom · Risky

The mu-opioid-receptor-active minor alkaloid of kratom, sold as concentrated powder, gummies, or shots ('7-OH', 'pure 7'). Ordinary kratom leaf contains ~2% mitragynine and trace 7-OH; concentrated 7-OH products bypass the leaf's safer alkaloid balance and produce stronger opioid agonism, withdrawal, and overdose risk. FDA has flagged emerging products. Avoid.

Dose: AVOID