Supplements and GLP-1 drugs: Ozempic, Wegovy, Mounjaro, Zepbound
Two different searches land here. One is from someone already prescribed semaglutide or tirzepatide who wants to know which supplements are worth thinking about. The other is from someone looking at a bottle that says GLP-1 on the label. Those are not the same question.
Which name is which drug
- Ozempic is injectable semaglutide used for type 2 diabetes.
- Wegovy is semaglutide used for weight management.
- Rybelsus is semaglutide as a tablet.
- Mounjaro is tirzepatide used for type 2 diabetes.
- Zepbound is tirzepatide used for weight management.
This page does not dose those drugs and does not quote a weight-loss percentage. The prescriber owns that. A supplement is not a substitute and not a booster that the trials above were built to test.
If you are already on one of the drugs
- Supplements on Ozempic, Wegovy, Mounjaro, and Zepbound
- Muscle
- Micronutrients
- Nausea and constipation
- Hair shedding
- What not to stack
- Psyllium with semaglutide or tirzepatide
If you are looking at a GLP-1 supplement
Start with Do GLP-1 supplements work? Berberine has type 2 diabetes glucose data. It has not been shown, in anything we read, to stand in for semaglutide or tirzepatide. Related comparisons: berberine vs metformin and berberine and the Ozempic nickname.
Questions people ask
Is a GLP-1 supplement the same as Ozempic, Wegovy, or Zepbound?
No. Those names, plus Rybelsus and Mounjaro, are prescription semaglutide or tirzepatide. The supplement is a different product using a borrowed word.
Do berberine or other GLP-1 supplements work like those drugs?
Berberine has lowered fasting glucose and HbA1c in type 2 diabetes meta-analyses. We did not read a trial against semaglutide or tirzepatide. Details and the numbers are in the reality-check article.