Zeaxanthin (standalone)
What it is
One of two oxygenated carotenoids concentrated in the central macula (the other is lutein), where it absorbs blue-light photons before they damage photoreceptor outer segments. The AREDS2 trial established 2 mg zeaxanthin plus 10 mg lutein daily as the optimal combination for slowing progression to advanced AMD in at-risk patients — roughly a 25% reduction in progression over five years. Modest effects on visual performance metrics and digital eye strain have also been reported. Extremely safe; excess is excreted without toxicity and minor harmless skin yellowing can occur at very high intakes.
Dose
2–4 mg/day standalone or as part of the AREDS2 combination (2 mg zeaxanthin + 10 mg lutein)
Time of day & tips
Take with a fatty meal — carotenoids are fat-soluble. Can be taken any time of day with food. Often combined with lutein in eye-health formulas.
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