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White willow bark (Salix alba)

Pain · Inflammation · Back pain
Tier 2 — Promising

What it is

Contains salicin, a natural precursor to aspirin. ESCOP approves it for back pain, osteoarthritis, and headache. A 2024 review found 240 mg salicin per day significantly reduces lower back pain. Gentler on the stomach than aspirin in most studies. Avoid in children under 16 due to theoretical Reye syndrome risk. Do not combine with blood thinners or NSAIDs.

Efficacy
3/5
Safety
3/5
Research
3/5
Onset
3/5
Cost
3/5
Drug-int.
3/5

Dose

240 mg salicin/day from standardised extract; avoid with aspirin, NSAIDs, and anticoagulants

Time of day & tips

Take with food and water. Do not combine with aspirin, ibuprofen, or blood thinners. Do not give to children under 16.

Sensitive populations: This supplement's evidence base touches pregnancy, pediatric, or other sensitive populations. Confirm any change with your healthcare provider before use.

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