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VSL#3 / Visbiome (multi-strain)

IBD · Pouchitis · Gut barrier
Tier 2 — Promising

What it is

A high-potency multi-strain probiotic with strong evidence for inflammatory bowel disease. Multiple trials show it induces and maintains remission in ulcerative colitis pouchitis. Contains 8 strains at 450 to 900 billion CFU per dose, far higher than typical probiotics. The original formula (now sold as Visbiome) has the clinical evidence — generics may not be equivalent. Requires refrigeration.

Efficacy
4/5
Safety
4/5
Research
3/5
Onset
3/5
Cost
2/5
Drug-int.
4/5

Dose

1–2 sachets/day (450–900 billion CFU); requires refrigeration; use Visbiome for original formula

Time of day & tips

Keep refrigerated at all times. Mix sachet into cool (not hot) food or drink. Take with a meal. Do not use the generic if clinical results are needed.

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