58
SCORE
Trehalose
Gut health · Autophagy · Neuroprotection
Tier 3 — Trending
What it is
A disaccharide found naturally in fungi, insects, and some plants with unique biological effects beyond simple nutrition. Oral trehalose acts as a prebiotic for Bifidobacterium, mildly activates cellular autophagy, and has shown neuroprotective effects in animal models of Parkinson's and Alzheimer's disease. Human data is limited to gut microbiome effects. Safety is excellent. Most dramatic benefits remain preclinical.
Efficacy
2/5
Safety
5/5
Research
2/5
Onset
2/5
Cost
3/5
Drug-int.
4/5
Dose
5–10 g/day in water or food
Time of day & tips
Can replace some sugar in drinks; mild sweetness; diabetics should account for it as a carbohydrate source
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