Taurine (cardiac and metabolic)
What it is
A conditionally essential amino sulfonic acid that regulates cellular hydration, mitochondrial function, and cardiac electrical stability. Circulating taurine declines by roughly 80% between young adulthood and late life. A 2024 meta-analysis of 20 randomised trials found 3–6 g/day lowered resting heart rate by ~3.6 bpm and blood pressure by ~4 mmHg. A 2023 Nature paper in aged mice and non-human primates linked taurine supplementation to improvements in multiple aging biomarkers, though the human healthspan trials are still years from reading out. Very safe at tested doses; avoid in bipolar mania.
Dose
500–3,000 mg/day in 2–3 divided doses; blood pressure effects are additive with antihypertensives
Time of day & tips
Take with meals split into 2–3 daily doses. If on blood pressure medication, monitor BP as effects are additive. Can be taken at any time of day.
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