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Sage extract (Salvia officinalis)

Cognition · Menopause · Blood sugar
Tier 3 — Trending

What it is

Shows cognitive-enhancing effects in small trials, with improved memory and attention in both young and older adults. Also reduces hot flash frequency and intensity during menopause. Contains thujone, which is neurotoxic at high doses, so long-term use of concentrated extracts requires caution. Culinary sage use is completely safe. May lower blood sugar and interact with diabetes medications.

Efficacy
2/5
Safety
3/5
Research
2/5
Onset
3/5
Cost
3/5
Drug-int.
3/5

Dose

300–600 mg/day standardised extract; avoid high doses long-term due to thujone content

Time of day & tips

Take with food. Limit to standard doses and avoid long-term use of concentrated extracts. Monitor blood sugar if on diabetes medication.

Sensitive populations: This supplement's evidence base touches pregnancy, pediatric, or other sensitive populations. Confirm any change with your healthcare provider before use.

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