69
SCORE
Rutin
Circulation · Varicose veins · Inflammation
Tier 2 — Promising
What it is
A plant flavonoid found in buckwheat, citrus fruits, and asparagus that strengthens blood vessel walls. Multiple European trials show it significantly reduces leg swelling and symptoms of chronic venous insufficiency. Works through anti-inflammatory pathways and by reducing capillary permeability. Very safe with an excellent tolerance profile and no serious side effects.
Efficacy
3/5
Safety
5/5
Research
2/5
Onset
2/5
Cost
4/5
Drug-int.
5/5
Dose
500–1,000 mg/day; often combined with hesperidin and vitamin C for vascular support
Time of day & tips
Take with food. Often combined with vitamin C for enhanced vascular effect. Timing is flexible — once daily with a meal is fine.
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