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Red clover (Trifolium pratense)

Menopause · Bone · Isoflavones

Tier 3 — Trending

What it is

Contains isoflavones that weakly mimic oestrogen, making it one of the more studied herbal options for menopause symptoms. A 2024 review of 11 trials found it significantly reduces hot flash frequency by about 40 percent after 12 weeks. Also shows modest bone density preservation in postmenopausal women. May interact with hormone-sensitive conditions and blood thinners. Not recommended for women with a history of breast cancer.

Efficacy

3/5

Safety

3/5

Research

3/5

Onset

2/5

Cost

3/5

Drug-int.

3/5

Dose

40–80 mg/day isoflavones from standardised red clover extract; avoid with hormone-sensitive cancers

Time of day & tips

Take with food. Avoid if you have a history of hormone-sensitive cancers or are on blood thinners. Morning dosing is fine. Allow 8–12 weeks for menopause benefits.

Sensitive populations: This supplement's evidence base touches pregnancy, pediatric, or other sensitive populations. Confirm any change with your healthcare provider before use.

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