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Pyruvate (calcium pyruvate)
Weight management · Endurance · Metabolism
Tier 3 — Trending
What it is
May help with modest fat loss by boosting cellular fat burning. A 2024 review of 6 trials found calcium pyruvate produces about 0.6 kg of fat loss. The effect is small but consistent across studies. High doses above 5 g per day commonly cause stomach discomfort. Not a significant weight loss solution on its own. Generally safe at moderate doses.
Efficacy
2/5
Safety
4/5
Research
2/5
Onset
3/5
Cost
2/5
Drug-int.
4/5
Dose
5–6 g/day in divided doses; GI discomfort common above 5 g — start at 2–3 g
Time of day & tips
Split across 2–3 doses taken with meals. Start at 2–3 g/day and increase slowly. Taking on an empty stomach commonly causes diarrhoea and bloating.
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