69
SCORE
Proline (L-Proline)
Collagen synthesis · Wound healing · Skin
Tier 2 — Promising
What it is
The primary structural component of collagen, making up about 28% of all collagen residues. Your body synthesises proline from glutamate, but supplementation alongside vitamin C and glycine may support collagen production after injury or during aging. Often included in collagen stacks. Very safe at standard doses.
Efficacy
3/5
Safety
5/5
Research
2/5
Onset
2/5
Cost
4/5
Drug-int.
5/5
Dose
500–2,000 mg/day alongside vitamin C and glycine for collagen synthesis support
Time of day & tips
Take with vitamin C for optimal collagen synthesis — they work together. Can be taken with or without food. Morning is a convenient time. Very safe at all tested doses.
Compare or learn more
Compare with another supplement →
Browse by symptom →
Open the full interactive view →