54
SCORE
Policosanol
Cholesterol · Cardiovascular
Tier 3 — Trending
What it is
Derived from sugar cane wax and marketed for cholesterol reduction. Cuban studies claimed dramatic cholesterol reductions, but every independent study conducted outside Cuba has consistently shown no significant effect. This is a notable example of research results that could not be replicated by other laboratories. Not recommended for cholesterol management.
Efficacy
2/5
Safety
4/5
Research
2/5
Onset
2/5
Cost
3/5
Drug-int.
4/5
Dose
10–20 mg/day; independent studies found no benefit — Cuban results not replicated
Time of day & tips
No strong intake guidance needed given the lack of evidence. If using, take with the evening meal as is traditional for cholesterol supplements.
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