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SCORE
Pine bark extract (Pycnogenol)
Circulation · Skin · Antioxidant
Tier 3 — Trending
What it is
A potent antioxidant extract from French maritime pine bark. Multiple small trials show improvements in poor leg circulation, skin elasticity, and blood vessel function. Contains similar active compounds to grape seed extract. Generally well tolerated with a good safety record. Most evidence comes from small, manufacturer-funded studies.
Efficacy
2/5
Safety
4/5
Research
2/5
Onset
2/5
Cost
2/5
Drug-int.
4/5
Dose
100–200 mg/day standardised extract (65–75% procyanidins)
Time of day & tips
Take with a meal containing fat for best absorption. Can be taken morning or afternoon.
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