65
SCORE
PharmaGABA
Stress · Sleep · Relaxation
Tier 2 — Promising
What it is
Produced by natural fermentation using Lactobacillus hilgardii, yielding a GABA form that may cross the blood-brain barrier better than synthetic GABA. Multiple trials show it reduces cortisol, increases alpha brain waves, and improves sleep. A 2024 review of 7 trials confirmed significant relaxation and sleep benefits.
Efficacy
3/5
Safety
4/5
Research
2/5
Onset
4/5
Cost
3/5
Drug-int.
4/5
Dose
100–200 mg/day PharmaGABA 30–60 min before bed or before a stressful event
Time of day & tips
Take 30–60 min before bed or before a stressful situation. Can be taken with or without food. Avoid combining with alcohol or sedative medications.
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