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SCORE
Peppermint oil (enteric-coated)
IBS · Gut motility · Pain
Tier 2 — Promising
What it is
One of the best-supported natural treatments for IBS. A 2024 review of 12 trials found enteric-coated peppermint oil significantly improves overall IBS symptoms including pain, bloating, and urgency. Must use enteric-coated capsules because regular peppermint oil won't survive stomach acid. Take 30 to 60 minutes before meals for best results.
Efficacy
4/5
Safety
4/5
Research
4/5
Onset
4/5
Cost
3/5
Drug-int.
4/5
Dose
0.2–0.4 mL enteric-coated capsule × 3 daily, 30–60 min before meals
Time of day & tips
Take 30–60 min before meals on an empty stomach. Do not crush or chew — swallow whole. Avoid antacids within 1 hour as they can dissolve the enteric coating too early.
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