58
SCORE
Nattokinase
Cardiovascular · Fibrinolysis · Blood pressure
Tier 3 — Trending
What it is
A natural enzyme from fermented soybeans that may support cardiovascular health. A 2024 review of 15 trials found nattokinase significantly lowers blood pressure by about 4.5 mmHg and reduces blood-clotting protein levels. Do not take with blood thinners like warfarin or aspirin, as the combined effect could cause dangerous bleeding.
Efficacy
3/5
Safety
3/5
Research
3/5
Onset
3/5
Cost
3/5
Drug-int.
2/5
Dose
2,000–4,000 FU/day (100–200 mg); AVOID with warfarin, aspirin, or other blood thinners
Time of day & tips
Take on an empty stomach for best activity. Avoid taking with blood thinners or aspirin — dangerous bleeding risk. Do not take with vitamin E or fish oil without medical guidance.
Compare or learn more
Compare with another supplement →
Browse by symptom →
Open the full interactive view →