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Mucuna pruriens (velvet bean)

Dopamine precursor · Mood · Movement

Tier 3 — Trending

What it is

Tropical legume whose seeds naturally contain L-DOPA, the immediate precursor to dopamine. Standardised extracts (typically 15–30% L-DOPA) have small clinical trials for early Parkinson disease symptoms and short-term mood / motivation effects in healthy adults. The natural-source L-DOPA is paired with native cofactors that may give a smoother pharmacokinetic profile than synthetic levodopa, but it is not a substitute for prescription Parkinson care. Caution alongside MAO-inhibitors and any dopaminergic medication.

Efficacy

3/5

Safety

3/5

Research

3/5

Onset

3/5

Cost

4/5

Drug-int.

3/5

Dose

200–500 mg of 15–30% L-DOPA standardised extract daily; PD trials use higher doses under physician supervision

Time of day & tips

Take on empty stomach for absorption; do NOT combine with prescription L-DOPA, MAOIs, or antipsychotics without specialist guidance; avoid in pregnancy.

Sensitive populations: This supplement's evidence base touches pregnancy, pediatric, or other sensitive populations. Confirm any change with your healthcare provider before use.

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