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Monolaurin

Antimicrobial · Immunity · Gut
Tier 3 — Trending

What it is

A coconut-derived monoglyceride with antimicrobial activity against enveloped viruses and gram-positive bacteria in lab studies. Very few human trials exist; most evidence is extrapolated from in vitro or lauric acid research. No rigorous RCTs confirm specific clinical benefits. Generally safe. Herxheimer-like reactions can occur early in use — start at a low dose.

Efficacy
2/5
Safety
4/5
Research
1/5
Onset
3/5
Cost
3/5
Drug-int.
5/5

Dose

600–1,800 mg/day; start low (300 mg) to avoid Herxheimer-like reactions

Time of day & tips

Start at 300 mg with food and increase slowly over 1–2 weeks. Take with food to reduce stomach upset. Flu-like symptoms at the start are common — reduce dose if severe.

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